Details for gene set NCI_IL12-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_04_DMpreB_versus_WTpreB.phenotype_DMpreB_versus_WTpreB.cls #DMpreB_versus_WTpreB
Phenotype	phenotype_DMpreB_versus_WTpreB.cls#DMpreB_versus_WTpreB
Upregulated in class	WTpreB
GeneSet	NCI_IL12-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.7255019
Normalized Enrichment Score (NES)	-1.6854573
Nominal p-value	0.0
FDR q-value	0.008402059
FWER p-Value	0.057

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	RAB7A	9684 5347 9683	788	1.027	-0.0155	No
2	CD86	1660 22601	1048	0.807	-0.0083	No
3	ARRB2	20806	1508	0.540	-0.0188	No
4	MAPK8	6459	1918	0.379	-0.0310	No
5	MALT1	6274	2207	0.289	-0.0389	No
6	CHUK	23665	2349	0.253	-0.0399	No
7	IL12RB1	3916 18582	2372	0.245	-0.0346	No
8	IKBKB	4907	2832	0.138	-0.0558	No
9	IL2RB	22219	3134	0.093	-0.0696	No
10	IL18R1	14263	3182	0.087	-0.0698	No
11	EOMES	4669	3344	0.073	-0.0766	No
12	IL1R1	14264 3987	3579	0.059	-0.0877	No
13	CD3D	19473	3844	0.046	-0.1007	No
14	IL1B	14431	3930	0.043	-0.1042	No
15	IL6ST	4920	3981	0.041	-0.1058	No
16	IL4	9174	4896	0.022	-0.1546	No
17	CD4	16999	5257	0.018	-0.1736	No
18	XPO1	4172	5368	0.017	-0.1791	No
19	FBXW11	20926	5630	0.015	-0.1928	No
20	SRC	5507	5732	0.014	-0.1979	No
21	IL27	17636	7244	0.007	-0.2793	No
22	IL12RB2	17128	7247	0.007	-0.2792	No
23	IL13	20461	7272	0.007	-0.2803	No
24	GATA3	9004	7432	0.006	-0.2888	No
25	FRAP1	2468 15991	7627	0.006	-0.2991	No
26	CD3E	8714	8078	0.004	-0.3233	No
27	CCL3	20317	8172	0.004	-0.3282	No
28	IL17A	14289	8270	0.004	-0.3333	No
29	IL2	15354	8581	0.003	-0.3500	No
30	CD28	14239 4092	8633	0.003	-0.3527	No
31	CD247	4498 8715	9037	0.002	-0.3744	No
32	B2M	72 14882	9090	0.002	-0.3771	No
33	ATM	2976 19115	9513	0.001	-0.3999	No
34	NFKB2	23810	9535	0.001	-0.4010	No
35	PRF1	20011	9734	0.000	-0.4117	No
36	CCL4	1362 20730	10317	-0.001	-0.4431	No
37	IL12B	20918	10475	-0.001	-0.4516	No
38	CCR5	8754 4534	10515	-0.001	-0.4536	No
39	IL6	16895	10534	-0.001	-0.4546	No
40	TBX21	20276	10857	-0.002	-0.4719	No
41	CD3G	19139	11521	-0.004	-0.5076	No
42	IKBKG	2570 2562 4908	11885	-0.005	-0.5271	No
43	GZMA	21343	12107	-0.006	-0.5389	No
44	IL18RAP	14262	12314	-0.007	-0.5498	No
45	PIK3R1	3170	12501	-0.008	-0.5597	No
46	RIPK2	2528 15935	12516	-0.008	-0.5602	No
47	GZMB	21810	12564	-0.008	-0.5625	No
48	SPHK2	1217 1806 12155	13294	-0.012	-0.6016	No
49	PIK3CA	9562	13536	-0.014	-0.6142	No
50	ATF2	4418 2759	13658	-0.015	-0.6204	No
51	TNF	23004	13662	-0.015	-0.6201	No
52	CD8B	4502 17418	13707	-0.016	-0.6221	No
53	CD80	22758	13913	-0.018	-0.6327	No
54	PIAS2	1948 5102	13991	-0.019	-0.6364	No
55	FASLG	13789	14495	-0.029	-0.6628	No
56	BCL3	8654	14526	-0.029	-0.6636	No
57	ERC1	1013 17021 995 1136	14611	-0.032	-0.6673	No
58	FOS	21202	14780	-0.038	-0.6754	No
59	IL2RG	24096	14967	-0.044	-0.6843	No
60	STAT4	14251 9907	14999	-0.046	-0.6848	No
61	STAT6	19854 9909	15003	-0.046	-0.6837	No
62	JAK2	23893 9197 3706	15078	-0.050	-0.6864	No
63	STAT5A	20664	15080	-0.050	-0.6851	No
64	TNFRSF1A	1181 10206	15409	-0.069	-0.7010	No
65	IFNG	19869	15440	-0.071	-0.7008	No
66	UBE2D3	7253	15448	-0.072	-0.6992	No
67	EBI3	23193	15451	-0.073	-0.6974	No
68	RELB	17942	15563	-0.083	-0.7012	No
69	IRF1	1336 1258 1433 9182	15764	-0.106	-0.7093	No
70	NOD2	6384	15923	-0.131	-0.7144	No
71	IL27RA	11949	15939	-0.133	-0.7117	No
72	REL	9716	16118	-0.172	-0.7168	No
73	LCK	15746	16281	-0.210	-0.7200	Yes
74	CYLD	18532	16309	-0.218	-0.7157	Yes
75	TYK2	12058 19215	16346	-0.228	-0.7116	Yes
76	MAP2K3	20856	16576	-0.300	-0.7161	Yes
77	JAK1	15827	16601	-0.307	-0.7093	Yes
78	GADD45G	21637	16864	-0.392	-0.7132	Yes
79	MAP2K6	20614 1414	16879	-0.397	-0.7035	Yes
80	PRKCA	20174	17118	-0.497	-0.7032	Yes
81	BIRC2	4397 4398	17163	-0.514	-0.6921	Yes
82	MAPK14	23313	17215	-0.531	-0.6809	Yes
83	STAT2	19840	17355	-0.605	-0.6724	Yes
84	GADD45B	19935	17372	-0.615	-0.6571	Yes
85	JUN	15832	17458	-0.677	-0.6439	Yes
86	IL2RA	4918	17525	-0.716	-0.6286	Yes
87	SOCS1	4522	17563	-0.738	-0.6111	Yes
88	NFKB1	15160	17596	-0.757	-0.5929	Yes
89	MAP3K14	11998	17649	-0.792	-0.5749	Yes
90	ETV5	22630	17725	-0.855	-0.5564	Yes
91	RELA	23783	17734	-0.859	-0.5342	Yes
92	SYK	21636	17870	-0.978	-0.5158	Yes
93	BCL10	15397	17878	-0.984	-0.4903	Yes
94	TRAF6	5797 14940	17908	-1.020	-0.4650	Yes
95	IL18	9172	18031	-1.145	-0.4414	Yes
96	TNFAIP3	19810	18051	-1.180	-0.4114	Yes
97	STAT1	3936 5524	18114	-1.257	-0.3816	Yes
98	CREBBP	22682 8783	18124	-1.271	-0.3486	Yes
99	NFKBIA	21065	18148	-1.309	-0.3154	Yes
100	STAT3	5525 9906	18327	-1.720	-0.2797	Yes
101	MAPK9	1233 20903 1383	18352	-1.775	-0.2343	Yes
102	IL12A	4913	18353	-1.783	-0.1874	Yes
103	TGFB1	18332	18378	-1.858	-0.1397	Yes
104	RAN	5356 9691	18611	-5.793	0.0003	Yes